Tadalafil 5mg

What is Cialis and how is it used?

  • Cialis is a prescription medicine used to treat the symptoms of erectile dysfunction. Cialis may be used alone or with other medications.
  • Cialis belongs to a class of drugs called Phosphodiesterase-5 Enzyme Inhibitors.
  • It is not known if Cialis is safe and effective in children.

Cialis may cause serious side effects including:

  1. chest pain,
  2. pain spreading to the jaw or shoulder,
  3. nausea,
  4. sweating,
  5. vision changes,
  6. sudden vision loss,
  7. ringing in your ears,
  8. sudden hearing loss, and
  9. an erection that is painful or lasts longer than 4 hours

Get medical help right away, if you have any of the symptoms listed above.

The most common side effects of Cialis include:

  • headache,
  • flushing (warmth, redness or tingly feeling),
  • nausea,
  • upset stomach,
  • runny or stuffy nose,
  • muscle pain,
  • back pain, and
  • pain in your arms or legs

Tell the doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Cialis. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

  • CIALIS (tadalafil) is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Tadalafil has the empirical formula C22H19N3O4 representing a molecular weight of 389.41. The structural formula is:
  • CIALIS (tadalafil) Structural Formula - Illustration
    The chemical designation is pyrazino[1';,2';:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-. It is a crystalline solid that is practically insoluble in water and very slightly soluble in ethanol.
  • CIALIS is available as almond-shaped tablets for oral administration. Each tablet contains 2.5, 5, 10, or 20 mg of tadalafil and the following inactive ingredients: croscarmellose sodium, hydroxypropyl cellulose, hypromellose, iron oxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, talc, titanium dioxide, and triacetin.
  • CIALIS is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH).
  • CIALIS is indicated for the treatment of ED and the signs and symptoms of BPH (ED/BPH).

If CIALIS is used with finasteride to initiate BPH treatment, such use is recommended for up to 26 weeks because the incremental benefit of CIALIS decreases from 4 weeks until 26 weeks, and the incremental benefit of CIALIS beyond 26 weeks is unknown . Do not split CIALIS tablets; entire dose should be taken.

CIALIS For Use As Needed For Erectile Dysfunction

The recommended starting dose of CIALIS for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity.
The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability. The maximum recommended dosing frequency is once per day in most patients.
CIALIS for use as needed was shown to improve erectile function compared to placebo up to 36 hours following dosing. Therefore, when advising patients on optimal use of CIALIS, this should be taken into consideration. The recommended starting dose of CIALIS for once daily use is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.
The CIALIS dose for once daily use may be increased to 5 mg, based on individual efficacy and tolerability. The recommended dose of CIALIS for once daily use is 5 mg, taken at approximately the same time every day. When therapy for BPH is initiated with CIALIS and finasteride, the recommended dose of CIALIS for once daily use is 5 mg, taken at approximately the same time every day for up to 26 weeks. 
The recommended dose of CIALIS for once daily use is 5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.

Creatinine clearance 30 to 50 mL/min: A starting dose of 5 mg not more than once per day is recommended, and the maximum dose is 10 mg not more than once in every 48 hours.
Creatinine clearance less than 30 mL/min or on hemodialysis: The maximum dose is 5 mg not more than once in every 72 hours. 

Creatinine clearance less than 30 mL/min or on hemodialysis: CIALIS for once daily use is not recommended.
Creatinine clearance 30 to 50 mL/min: A starting dose of 2.5 mg is recommended. An increase to 5 mg may be considered based on individual response.
Creatinine clearance less than 30 mL/min or on hemodialysis: CIALIS for once daily use is not recommended .

Four strengths of almond-shaped tablets are available in different sizes and different shades of yellow:

  • 2.5 mg tablets debossed with “C 2½”
  • 5 mg tablets debossed with “C 5”
  • 10 mg tablets debossed with “C 10”
  • 20 mg tablets debossed with “C 20”